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Fundamentals of Nursing
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Chapter 28 Infection Control
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Chapter 28 Infection Control

🦠 Colonization vs. Infection

Feature
Colonization
Infection
Definition
Microorganisms are present on or in the body but not causing harm.
Microorganisms invade tissues, multiply, and cause damage or symptoms.
Immune Response
No immune reaction or tissue damage.
Active immune response → inflammation, pus, fever, pain.
Symptoms
None (asymptomatic).
Present — fever, redness, swelling, drainage, pain.
Contagious?
Can still spread to others even without symptoms.
Often contagious depending on organism and infection site.
Example
MRSA on skin or in nose without illness.
MRSA wound infection causing redness and drainage.

🧠 Quick Tip:

“Colonization = germs living there 🏠 — no problem yet.”

“Infection = germs attacking ⚔️ — body fights back.”

🦠 Chain of Infection (Must Know!)

  1. Infectious Agent
  2. Reservoir
  3. Portal of Exit
  4. Mode of Transmission
  5. Portal of Entry
  6. Susceptible Host

🧠 Breaking any link prevents infection.

🦠 Types of exudate (Must Know!)

  • Serous: Clear, thin, and watery fluid that is typically seen in the early stages of healing.
  • Sanguineous: Bright red fluid that is mainly composed of blood.
  • Serosanguineous: Pink or reddish fluid that contains a small amount of blood.
  • Purulent: Formation of Pus. Thick, yellow, green, or white fluid that contains pus, which is a mixture of dead white blood cells, bacteria, and debris.
  • Mixed: A combination of different types of exudate.

🩸 Modes of Transmission

Type
Example Diseases
PPE/Precautions
Contact
MRSA, C. difficile
Gloves, gown
Droplet
Influenza, meningitis
Mask, gloves
Airborne
TB, measles, COVID
N95 respirator, negative-pressure room
Indirect
Contaminated surfaces or instruments
Hand hygiene + disinfection

🧍 Inflammation & Defense

  • Signs: redness, heat, swelling, pain, loss of function.
  • Learn Table 28.2 (body defenses).
  • Stages of infection:
    1. Incubation – pathogen enters, no symptoms.
    2. Prodromal – mild, vague symptoms. nonspecific signs and symptoms and patient may be capable of spreading disease to others
    3. Illness – severe symptoms. signs and symptoms specific to type of infection
    4. Convalescence – recovery phase.

🏥 Health-Care–Associated Infections (HAIs)

  • Caused by poor asepsis or cross-contamination.
  • Nosocomial diseases = healthcare-associated infections (HAIs)
  • High-risk patients: elderly, malnourished, immunocompromised, post-surgery.
  • Common sources: catheters, suction, BP cuffs, uncleaned equipment.
  • Always use dedicated equipment for isolation patients.

🏥 Health Care–Associated Infections (HAIs)

Type
Source
Example
Iatrogenic
From a procedure
Catheter-associated UTI
Exogenous
From outside microorganisms
MRSA, Salmonella
Endogenous
From altered patient flora
Yeast infection after antibiotics

🧠 Prevention: Hand hygiene, aseptic technique, clean or single-patient equipment.

💊 Antibiotics

  • Overuse can weaken immune defenses or cause resistance.
  • Monitor for superinfection (e.g., yeast infection after antibiotics).

🩹 Asepsis & Cleaning

  • Medical asepsis: “clean technique.”
  • Surgical asepsis: “sterile technique.” Used for invasive procedures and open wounds.
  • Pouring liquids: Avoid splashing; keep sterile field dry.
  • Clean from clean → dirty areas.
  • Use PPE appropriate to the situation.
  • Disinfect with bleach, alcohol wipes, or CaviWipes.
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😷 Cough Etiquette

  • Cover mouth/nose with tissue or elbow when coughing.
  • Dispose of tissue and perform hand hygiene immediately.
  • Wear a mask if coughing near others.
  • Keep 3 feet (1 meter) distance from others if symptomatic.

🧍‍♀️ Patient Communication & Education

  • Introduce yourself when wearing a mask (patients can’t see your face).
  • Teach patients about handwashing, vaccination, and infection prevention.
  • Include travel history in assessment for infectious diseases.

📋 Nursing Process for Infection

  • Diagnosis examples:
    • Risk for Infection
    • Impaired Tissue Integrity
    • Social Isolation
  • Goals (SMART): control infection spread, reduce symptoms, verbalize prevention methods.
  • Team approach: nurses, providers, infection control, and patient/family.

🧫 Infection Control & Surgical Asepsis — Study Guide

🦠 Communicable Diseases

  • Communicable disease: Infection transmitted from one person to another.
  • Symptomatic: Clinical signs and symptoms are present.
  • Asymptomatic: No signs or symptoms, but infection can still spread.

🧠 Example: COVID-19 and hepatitis B can both be asymptomatic yet contagious.

🧍 Body’s Cellular Response to Infection or Injury

  1. Vascular & Cellular Response: Blood vessels dilate → ↑ blood flow → redness, heat, swelling.
  2. Inflammatory Exudate: Fluid, pus, or drainage containing WBCs and debris collects at injury site.
  3. Tissue Repair: Damaged tissue replaced with new cells (regeneration or scar formation).

🧠 Goal: Contain infection and promote healing.

🩺 Nursing Diagnoses Related to Infection

  • Risk for Infection
  • Imbalanced Nutrition: Less Than Body Requirements
  • Impaired Oral Mucous Membrane
  • Risk for Impaired Skin Integrity
  • Social Isolation
  • Impaired Tissue Integrity
  • Readiness for Enhanced Immunization Status

🧠 Plan goals that reduce exposure, control infection spread, and support immune function.

🧴 Disinfection vs. Sterilization

Process
Purpose
Kills Spores?
Examples
Disinfection
Eliminates many or all microorganisms (not spores) from inanimate objects
❌
Alcohol, bleach, CaviWipes
High-Level Disinfection
For critical equipment (e.g., endoscopes)
⚠️ Some
Glutaraldehyde, hydrogen peroxide
Sterilization
Destroys all microorganisms including spores
✅
Steam autoclave, ethylene oxide gas

🧠 Always sterilize instruments that enter sterile body areas.

🩹 Surgical Asepsis (Sterile Technique)

Purpose

  • Prevents contamination of open wounds.
  • Isolates the operative area from unsterile environments.
  • Maintains a sterile field for invasive procedures.

🧠 Used in: surgery, catheter insertion, sterile dressing changes, suctioning lower airway.

🧾 Sterile Field

  • A clean, prepared area free of microorganisms to receive sterile items.

⚖️ Principles of Surgical Asepsis

  1. A sterile object remains sterile only when touched by another sterile object.
  2. Only sterile items go on a sterile field.
  3. Anything below waist level or out of sight is contaminated.
  4. Prolonged air exposure contaminates a sterile field.
  5. Moisture contaminates by capillary action (keep surfaces dry).
  6. Fluids flow downward — hold hands above elbows when scrubbing.
  7. Edges (1 inch) of a sterile field are considered contaminated.

🧠 Tip: If in doubt, consider it contaminated and replace it.